Research areas
Electrochemistry and Boneintegration
Study Objective:
Create in titanium implants an oxide surface with good adherence, that
allows resistance to combined mechanical efforts, in addition to an
adequate thickness to avoid ionical conduction between tissue and the
implanted specimen.
The development of this oxide surface can be obtained by chemical,
physical and mechanical media. In this study it was realized through
electrochemical methods because these allow, abid certain parameters to
regulate oxide formation.
The parameters involved en the process of electrochemical formation of an
oxide surface are:
- Composition of the electrolytical solution.
- Variation of the electrical potencial applied.
- Temperature and fluid-dynamical conditions.
These procedures allowed to form an oxide surface varying between 50 and
500 Â in implants that were installed in rabbit tibia
for the study of boneintegration.
Complementarily a study on implants surface characterization was made to
compare the chemical states of oxide surfaces different thicknesses of
prototypes through Auger electron spectroscopy technique (AES).
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GBR
Guided Bone Regeneration using PLA/PGA copolymer membranes was studied on
rabbit tibia. Osteotomies were done at the proximal tibia metaphysis level
and some membranes were microfixed. Radiological results showed consolidation
signs after thirty days that accentuated with time during the experience.
After six months, uniform compact bone tissue was macroscopically observed
at microfixed osteotomies sites. A bone surface depletion was observed at non
microfixed membrane sites. Haversian bone formation, osteoid and fibrous
tissue, and remains of PLA/PGA membranes with slightly inflammatory edematous
tissue was observed in every sample.
Results suggest that microfixation prevents membrane collapse. Even though
bone healing occurred after six months in every sample, PLA/PGA membranes
were not completely reabsorbed in that time.
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